2021

Combined epigenetic and metabolic treatments overcome differentiation blockade in acute myeloid leukemia

Barry M. Zee, Kamrine E. Poels, Cong-Hui Yao, Kimihito C. Kawabata, Gongwei Wu, Cihangir Duy, William D. Jacobus, Elizabeth Senior, Jennifer E. Endress, Ashwini Jambhekar, Scott B. Lovitch, Jiexian Ma, Abhinav Dhall, Issac S. Harris, M. Andres Blanco, David B. Sykes, Jonathan D. Licht, David M. Weinstock, Yang Shi. Science Direct. June 25, 2021. DOI: 10.1016/j.isci.2021.102651

Low-cost transcriptional diagnostic to accurately categorize lymphomas in low- and middle-income countries

Fabiooa, Valvert, Oscar Silva, Elizabeth Solórzano-Ortiz, Maneka Puligandla, Marcos Mauricio Siliézar Tala, Timothy Guyon, Samuel L Dixon, Nelly López, Francisco López, César Camilo Carías Alvarado, Robert Terbrueggen, Kristen E Stevenson, Yasodha Natkunam, David M Weinstock, Edward L Briercheck​. National Library of Medicine. May 25, 2021. DOI: 10.1182/bloodadvances.2021004347

IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells

Jaewoong Lee, Mark E Robinson, Ning Ma, Dewan Artadji, Mohamed A Ahmed, Gang Xiao, Teresa Sadras, Gauri Deb, Janet Winchester, Kadriye Nehir Cosgun, Huimin Geng, Lai N Chan, Kohei Kume, Teemu P Miettinen, Ye Zhang, Matthew A Nix, Lars Klemm, Chun Wei When, Vishal Khairnar, Arun P Wiita, Andrei Thomas- Tikhonenko, Michael Farzan, Jae U Jung, David M Weinstock, Scott R Manalis, Michael S Diamond, Nagarajan Vaidehi, Markus Muschen. National Library of Medicine. April 12, 2021. DOI: 10.1038/s41586-021-03388-4

Genomic landscape of cutaneous follicular lymphomas reveals 2 subgroups with clinically predictive molecular features

Xiaolong Alan Zhou, Jingyi Yang, Kimberly G Ringbloom, Maria Estela Martinez-Escala, Kristen E Stevenson, Alexander T Wenzel, Damiano Fantini, Haley K Martin, Andrea P Moy, Elizabeth A Morgan, Shannon Harkins, Christian N Paxton, Bo Hong, Erica F Anderson, Joan Guitart, David M Weinstock, Lorenzo Cerroni, Jaehyuk Choi, Abner Louissaint. National Library of Medicine. February 9, 2021. DOI: 10.1182/bloodadvances.2020002469

RAS-protein activation but not mutation status is an outcome predictor and unifying therapeutic target for high-risk acute lymphoblastic leukemia 

David Koschut, Debleena Ray, Zhenhua Li, Emanuela Giarin, Jurgen Groet, Ivan Alic, Shirley Kow-Yin Kham, Wee Joo Chng, Hany Arrifin, David M Weinstock, Allen Eng-Juh Yeoh, Giuseppe Basso, Dean Nizetic. National Library of Medicine. January 28, 2021. DOI: 10.10.38/s41388-020-01567-7